Stephen with Professor John Quinn and Ben Middlehurst from the project “From Biology to Quality of Life with MND”.
![](https://darbyrimmermnd.co.uk/wp-content/uploads/2023/10/IMG_20551.jpg)
Our Research
Since the Darby Rimmer MND Foundation launched in October 2019, one of our
main aims was to fund research into MND. Below is a list of research projects we have
been able to fund thanks to our incredible supporters.
2021
Project: Understanding nutrition in MND
Lead Applicant: Professor Chris McDermott
Amount: £50,333
Duration: 2 years
Project: Development, validation and application of a novel multiplexed cell-based
drug screening assay to discover novel drug candidates focused on restoring protein
homeostasis in C9ALS/FTD
Lead Applicant: Professor Pam Shaw and Professor Kurt De Vos
Amount funded: £137,585
Duration: 2 years
Project: Professor John Quinn
Lead Applicant: From biology to quality of life in MND
Amount funded: £60,356.82
Duration: 1 year
2022
Project: Target identification of oxidative stress response-modifying drugs in an ESC-derived motor neuron model of ALS
Lead Applicant: Professor Kevin Talbot
Amount funded: £79,991.29
Duration: 1 year
Project: Professor John Quinn
Lead Applicant: From biology to quality of life in MND
Amount funded: £195,149.68
Duration: 2 years
Project: Investigating the role of mitochondrial variants in Amyotrophic Lateral
Sclerosis
Lead Applicant: Dr Alfredo Iacoangeli
Amount funded: £102,399.48
Duration: 2 years
Project: Integration of epigenetic profile in MND clinical trials
Lead Applicant: Professor Ammar Al-Chalabi and Dr Ahmad Khleifat
Amount funded: £83,376.84
Duration: 18 months.