Research

Stephen with Professor John Quinn and Ben Middlehurst from the project “From Biology to Quality of Life with MND”.

Since the Darby Rimmer MND Foundation launched in October 2019, one of our
main aims was to fund research into MND. Below is a list of research projects we have
been able to fund thanks to our incredible supporters.

2021

Project: Understanding nutrition in MND
Lead Applicant: Professor Chris McDermott
Amount: £50,333
Duration: 2 years

Project: Development, validation and application of a novel multiplexed cell-based
drug screening assay to discover novel drug candidates focused on restoring protein
homeostasis in C9ALS/FTD
Lead Applicant: Professor Pam Shaw and Professor Kurt De Vos
Amount funded: £137,585
Duration: 2 years

Project: Professor John Quinn
Lead Applicant: From biology to quality of life in MND
Amount funded: £60,356.82
Duration: 1 year

2022

Project: Target identification of oxidative stress response-modifying drugs in an ESC-derived motor neuron model of ALS
Lead Applicant: Professor Kevin Talbot
Amount funded: £79,991.29
Duration: 1 year

Project: Professor John Quinn
Lead Applicant: From biology to quality of life in MND
Amount funded: £195,149.68
Duration: 2 years

Project: Investigating the role of mitochondrial variants in Amyotrophic Lateral
Sclerosis
Lead Applicant: Dr Alfredo Iacoangeli
Amount funded: £102,399.48
Duration: 2 years

Project: Integration of epigenetic profile in MND clinical trials
Lead Applicant: Professor Ammar Al-Chalabi and Dr Ahmad Khleifat
Amount funded: £83,376.84
Duration: 18 months.